A 6-year time series of remotely-sensed global ocean chlorophyll was evaluated using linear regression analysis to assess recent trends. Global ocean chlorophyll has increased 4.1% (P < 0.05). Most of the increase has occurred in coastal regions, defined as bottom depth < 200 m, where an increase of 10.4% was observed. The main contributors to the increase were the Patagonian Shelf, Bering Sea, and the eastern Pacific, southwest African, and Somalian coasts. Although the global open ocean exhibited no significant change, 4 of the 5 mid-ocean gyres (Atlantic and Pacific) showed declines in chlorophyll over the 6 years. In all but the North Atlantic gyre, these were associated with significant increases in sea surface temperature in at least one season. These results suggest that changes are occurring in the biology of the global oceans.