Recent satellite observations show that a layer of haze perpetually hangs over the Pearl River Delta (PRD) region and surface observations show numerous violations of the Hong Kong Air Quality Objective. This layer of haze mostly concentrates in the Pearl River Estuary and a narrow (20 km wide) band along the shoreline, in particular during weak wind situations. Although researchers suspect the land-sea breeze (LSB) circulations “concentrate” or “trap” various pollutants in this region, the physical mechanism of the phenomenon has never been fully explained or quantified. In this paper, a mesoscale atmospheric model (MM5) coupled with the Noah land surface model (LSM), which has bulk urban land use treatments along with a detailed Pearl River Delta land use map, is used to investigate the unique feature and mechanism of this land-sea breeze effect and the temporal evolution. A three-dimensional particle trajectory model is used to understand its associated pollutant transport, trapping and accumulation. A conceptual model is then developed for the perpetual air pollution phenomenon in the region. Further sensitivity experiments are used to illustrate the impact of urbanization and large-scale winds on the pollution processes. Results show that urbanization enhances the pollutant trapping and therefore contributes to the overall poor air quality in the region.