Multiple environmental pathways have emerged from the climatic variability and extreme weather events, which have affected the state of well-being of human health. These phenomena have affected the spatiotemporal distribution of vector-borne diseases, water borne-diseases, and air-borne diseases through the influence on vectors by making the hosts more susceptible to diseases. This session will provide a platform to discuss the impacts of enhanced climatic variability on the spatiotemporal movement of diseases and the development of early warning systems.